Id been taking the normal dose of folic acid for months before and during that pregnancy. A concern of taking synthetic folic acid is that it may competitively interfere with bioactive folate, since folic acid binds more easily to receptors in your tissue. I received my thrombophilia work up, the gynae said there was no problem, despite the fact that they were positive, as I was only hetero (for 3 different mutations). Please let me know your opinions. to prevent recurrence ; also dose recommended for women who are: receiving anti-epileptic medication (1) or ; who have diabetes (2) or; who have sickle cell disease (3) or Folic acid is used to treat folic acid deficiency and certain types of anemia. During this time I was also diagnosed with a vit D deficiency which I was treated for over a week of high dose tablets, and also started low dose aspirin from BFP. "This is very encouraging data that suggest we may be reducing the risk of spontaneous abortions in the U.S. by fortifying certain foods," study researcher James L. Mills, MD, an NICHD epidemiologist, tells WebMD. I did not take any, and had 5 miscarriages. Folic acid is a B vitamin that is needed to make health y new cells. Many breakfast cereals, rice, pasta, and most breads are now an excellent source of the vitamin, as are beans, leafy green vegetables, and citrus fruits. "Our study did not show any increase in spontaneous abortions at all, in fact it went in the opposite direction," Mills says. Folic acid rapidly appears in the blood, where it is extensively bound to plasma proteins. Methyltetrahydrofolate reductase (MTHFR) is the enzyme that helps to turn folic acid into its active methyl-folate form. Relatively nontoxic. Saw a haematologist two days ago who confirmed this and said that my chances of carrying a pg untreated are lower than 10%, while with treatment (injections) they can go up to 80%! "That is extremely reassuring.". These birth defects include the paralyzing spinal disease spina bifida, and anencephaly, a fatal disease in which the brain does not develop. In the group of women with low folate levels a miscarriage was significantly more likely to occur if the fetus had an abnormal chromosome. Researchers compared 468 women who had miscarriages between six and 12 weeks of their pregnancies with 921 women who were also in their first trimester, but had not miscarried. After we eat folate or folic acid, the majority is converted into 5-MTHF before it enters the bloodstream, this metabolic process differs slightly between folate and folic acid. It is quite a common defect apparently (60% of the pop can have such a mutation) but it can cause problems in pregnancy (which is on its own a hypercoagulative condition= blood clots more in pg). After my fourth miscarriage I was prescribed 5mg folic acid which I started taking 3 months before I conceived again. I am now 5 weeks into my pregnancy and have my first prenatal appt. Hey, Have a question about folic acid just wondered if anyone can help. TTC After Miscarriage. The finding suggests that a 1998 mandate by the U.S. Food and Drug Administration to fortify grain products with folic acid (the synthetic form of the vitamin) may prevent miscarriage in some women, in addition to lowering their risk for having a child with a class of birth defects known as … The recommended daily intake of folic acid for all women of childbearing age is at least 400 micrograms (mcg), or 0.4 milligrams (mg). What is folic acid and where can I get it? In 1998, the FDA began requiring food manufacturers to fortify certain grain products with folic acid. Investigational treatments for COVID-19. Folic Acid or Prenatal Vitamin: I miscarried last Nov 27/13 and I stopped taking my folic acid because I figured I'm not pregnant anymore but just a few weeks ago I realized that I should continue taking the folic acid since my husband and I will be ttc next month. Ju1es sorry for your losses and everything you have been through! However, I had a thorough look as I wanted to know for myself and found that 2 of the three mutations I have can cause rec miscarriage and other pregnancy complications. I found out after my first mc that my little one had spina bifida. Third miscarriage was much earlier and I had a natural mc. (5) Unlike folate from food, the process of converting synthetic folic acid to the active form of vitamin … These effects may in part be responsible for the increased risk of miscarriage. Animals were fed on the diets for 3 weeks. Like you, all my tests came back clear for any problems. Should I be taking 400 mcg or 800mcg I was wondering if i took more if it would help our chances since I had a miscarriage (2weeks pregnant) a few weeks ago. Women who get at least 400 micrograms of the vitamin from their diets during the first few weeks of pregnancy can reduce their unborn baby's risk of neural tube defects (NTDs) by as much as 70%. The new findings refute a handful of earlier studies linking high folic acid consumption to an increase in miscarriages. Folic acid is used in combination with other medications to treat vitamin B12 deficiency (can lead to pernicious anemia). This is page 1 of 1 (This thread has 3 messages.). I started to mc naturally last Thursday which I should have been just over 7 weeks.My consultant has now advised a prescription of 5mg folic acid and to continue taking low dose aspirin. Women need to take folic acid every day and It is still unbelievable, as I never thought I would have another baby again, but I am confident that the influx of one of the vitamins I increased in my diet helped this baby stick.Hope everything works out for you in the future. During this time I was also diagnosed with a vit D deficiency which I was treated for over a week of high dose tablets, and also started low dose aspirin from BFP.I think escape has explained the use of folic acid in women with the MTFHR gene really well. If we do not have enough folic acid, the body can make abnormally large red blood cells that do not work properly. Just wondering if anyone knows how much folic acid is too much? 5mg folic acid? © 2005 - 2019 WebMD LLC. "One of the easiest ways to do this is to take either a multivitamin or a folic acid or B-vitamin supplement every day if there is any chance at all of becoming pregnant.". I was on folate with my first pregnancy but my doctor switched me to 5mg folic acid after my second miscarriage. In the latest study, women with inadequate folate levels were 50% more likely to have early pregnancy losses, but those with high folate levels did not have a greater miscarriage risk. At which stage I was already in the early stages of pregnancy again and unfortunatly mc 24 December.After a few horible cycles Jan, Feb, March my body started to repare itself. I had done all the tests from the fertility doctor and he mentioned in little detail that I had mthfr c677t homozygous & told me that this just meant my body had an enzyme that depletes folic acid and I was to increase my dose on top of my prenatal vitamins to 5mg a day. I'm taking normal vitamins in the morning but s I'm going to say about 97% of people can't cook. I have learned my lesson - sometimes you need to take charge of your treatment and chase dr's up - not all of them know everything. You may have a higher risk if: you have diabetes; you or your partner have a neural tube defect; you have had a previous pregnancy affected by a neural tube defect 1]) is based on a large number of women with well-documented, highly compliant use of folic acid 3 and gives us a good estimate of the rate of miscarriage among women who took folic acid. I got our results back beginning December which came back clear, he advised to take low dose apirin! This is really important in early pregnancy, and even before conception.Although I don't have any clotting disorders, I had to personally ask for the high dose folic acid from my GP, as I had done my research into it beforehand.In saying all the above, I don't know whether it has been the low dose aspirin, the high dose folic acid or the vitamin D deficiency being treated, but something worked and I am currently 22 weeks pregnant. All rights reserved. Top Treatment Tips, The D&C (Dilation and Curettage) Procedure. Folic Acid 5mg Tablets are used in the treatment and prevention of certain types of anaemia (low red blood cells), e.g. After having my daughter in 2009, I have since had 3 miscarriages and am now 7 weeks pregnant again. The study, published this week in the Journal of the American Medical Association, was conducted by researchers from Sweden's Karolinka Institute in conjunction with the U.S. National Institute of Child Health and Human Services (NICHD). If a woman has enough folic acid in her body before and during pregnancy, her baby is less likely to have an NTD. Babies with this defect die before birth (miscarriage) or shortly after birth. Not have enough folic acid rapidly appears in the production of red blood cells and iron utilization it. Levels of folate is in the treatment and prevention of certain types of anaemia ( red. Had blood tests done and all came back clear, he advised to take low apirin! 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